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The Effectiveness of Nutritional Support on the Metabolism of Patients with Alcohol Withdrawal

Journal «MEDICINA» ¹ 4, 2023, pp.79-89 (Research)


Utkin S. I.
MD, PhD1, Associate Professor, Chair for Psychiatry and Addictions2

Nenasteva A. Yu.
MD, PhD1, Associate Professor, Chair for Psychiatry and Addictions2

1 - Moscow Research and Practical Centre on Addictions, Moscow, Russian Federation
2 - I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russian Federation

Corresponding Author

Nenasteva Anna; e-mail: nenasteva_a_yu@staff.sechenov.ru

Conflict of interest

Authors have no conflict of interest.


The study received financial support from Fresenius Kabi LLC


In the article we present the results of a study of the effectiveness and safety of nutritional support for patients with alcohol withdrawal with a specialized food product «Glutamine-plus». An intergroup comparison of patients who received and did not receive «Glutamine-plus» was carried out according to the following parameters: clinical characteristics and metabolic features, including its dynamics during observation. Analysis of the data obtained showed that the addition of «Glutamine-plus» to a standard diet significantly improved metabolic processes, affected tissue respiration and more effectively restored the acid-base state in patients with alcohol withdrawal. Intake of «Glutamine-plus» also had a positive effect on the reduction of clinical manifestations of alcohol withdrawal and craving.

Key words

alcohol withdrawal syndrome, glutamine, metabolism, energy metabolism



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