Study of the Component Composition of the Mentha Asiatica Essential Oil by Gas Chromatography–Mass Spectrometry

Mashchenko P. S.
PhD (Pharmacy), Associate Professor, Chair for Toxicological Chemistry¹
ORCID 0000-0002-2259-7659

Sakhratov V. A.
Postgraduate Student¹
ORCID 0000-0002-4591-8099

Kalikina I. Yu.
Postgraduate Student¹
ORCID 0000-0002-4495-0118

Malkova T. L.
Doctor of Pharmaceutical Sciences, Professor, Head, Chair for Toxicological Chemistry¹
ORCID 0000-0002-5795-0803

1 - Perm State Pharmaceutical Academy, Perm, Russian Federation

Kalikina Irina; e-mail: kalikinaira@yandex.ru.

None declared.

The study was carried out with the financial support of the Perm Scientific and Educational Center «Rational Subsoil Use», 2022.

Medicinal plant raw materials have always been actively used in traditional and folk medicine. This is due to the wide range of medicinal plants therapeutic effect. Due to its therapeutic effect, Mentha asiatica Boriss is widely applied in the Republic of Tajikistan. It is used in the treatment of headaches, respiratory diseases and gastrointestinal tract disorders. To achieve the necessary level of pharmacological effect, it is necessary to take into account that the component composition of biologically active substances can change at different stages of plant development. Therefore, the aim of the study was to determine the component composition of Mentha asiatica essential oil at the stage of budding and flowering. Materials and methods: Samples of the Mentha asiatica essential oil were obtained during budding and flowering to conduct the study by method 1 of the State Pharmacopoeia XIV edition. The chemical composition of Mentha asiatica essential oils was studied by gas-liquid chromatography-mass spectrometry on Agilent 7890 A gas chromatograph with Agilent 5975C mass-selective detector. As a result, components such as limonene, eucalyptol, menthone, pulegone and isopulegone were found in the essential oil of flowering Mentha asiatica. Limonene, caryophyllene, carvone, trans-dihydrocarvone, and beta-bourbonene were found in samples of Mentha asiatica essential oil at the budding stage. It was found that all identified biologically active compounds have a wide range of therapeutic effects. Therefore, detailed studies of the Mentha asiatica essential oils pharmacological activity are of importance.

Mentha asiatica, essential oil, gas-liquid chromatography-mass spectrometry

10.29234/2308-9113-2022-10-2-34-40

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