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Δ9-desaturases in the regulation of exchange processes

Journal «MEDICINA» ¹ 2, 2021, pp.1-17 (Reviews)

Authors

Chuprov A. D.
Professor, Doctor of Medical Science, Director1

Kim S. M.
Ophthalmologist, Head of the Ophthalmological Department1

Kazakova T. V.
junior researcher2

Treushnikov V. M.
General Director3

1 - Orenburg branch of the S. Fyodorov Eye Microsurgery Federal State Institution of the Ministry of Health of the Russian Federation, Orenburg, Russia
2 - Federal Scientific Center for Biological Systems and Agricultural Technologies of the Russian Academy of Sciences, Orenburg, Russia
3 - OOO «Research and Development enterprise »Reper-NN«», Nizhniy Novgorod, Russia

Corresponding Author

Kim Svetlana Mikhailovna, e-mail: nauka@mail.ofmntk.ru

Funding

The study had no sponsorship.

Conflict of interest

None declared.

Abstract

Lens opacity, which leads to cataract, is one of the most complicated issues in ophthalmology. Pathophysiology of cataract progression is far from being clearly established. Despite low lipid content in the lens of the eye, there is an assumption that they and their predecessors may be involved in the development of this disease. Given the many roles of monounsaturated fatty acids, it can be expected that variations in stearoyl-Coa desaturase activity will affect a number of key physiological processes.

Key words

δ9 desaturases, stearoyl-Coa desaturase, cataract, lipid metabolism, eye lens

DOI

References

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