Study of Factors Affecting the Release of Drugs From Ointments

Erofeeva L. N.
Doctor of Pharmacy, Professor, Chair fop Pharmaceutical Technologies¹

Suchkina D. A.
Student¹

1 - Kursk State Medicine University, Kursk, Russia

Corresponding Author: Erofeeva Lija; e-mail: lnerofeeva@rambler.ru. Conflict of interest. None declared. Funding. The study had no sponsorship.

The results of experimental studies of pharmaceutical factors affecting the release of drugs from ointments using seven ointment bases and model drugs: salicylic acid, insoluble in bases and water, and resorcinol, soluble in water, glycerol and fatty oils are presented. The method of diffusion in gelatin gel showed that the main factors affecting the release of drugs from ointments are the basis and technology. The most rapid and complete release of the active substances occurred from 5% gel sodium carboxymethylcellulose.

ointments, bases for ointments, technology, salicylic acid, resorcinol

10.29234/2308-9113-2019-7-4-34-42

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