Significance of melatonin for the liver activity

Arushanyan E. B.
Doctor of Medicine, Professor, Head, Chair for Pharmacology¹

Shchetinin E. V.
Doctor of Medicine, Professor, Head, Chair for Pathophysiology¹

1 - Stavropol State Medical University

Evgeny V. Shchetinin; e-mail: ev.cliph@rambler.ru

None declared.

Recent experimental and clinical data about role of pineal and extrapineal melatonin for physiology and pathology of the liver are reviewed. Melatonin is involved in the control of the basic physiological functions of the liver, providing a modulating effect. The results of experimental studies indicate the presence of a distinct hepatoprotective effect of the hormone in various types of organ pathology. This allows one to assume the possibility of using melatonin in clinical settings for the prevention and treatment of various hepatic diseases.

melatonin, liver physiology and pathology

10.29234/2308-9113-2018-6-2-35-50

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