Authors
Shabalkin I. P.
Grigoreva E. Yu.
Stukalov Yu. V.
Shabalkin P. I.
NN Blokhin Russian Cancer Research Center, Moscow
Abstract
Evolution of the life is a natural result of constant changes in the gene pool. The latter circumstance leads to reorganization of the genes, caused not only by point mutations, but also by a violation of metabolic processes in the organism, which contribute to the appearance of new characters from the evolutionary point of view. The molecular mechanisms of this process are connected and depend directly on the features of the DNA structure proposed by D. Watson and F. Crick. At the present time, a new model for the structural organization of DNA is proposed, based on a mathematical pattern known as the Fibonacci number series. According to the latter, polymerization in the framework of the DNA chain leads to the formation of different types of dimers. The presence of different types of dimers determines the possibilities for the participation of the organism in the processes of evolution.
Key words
variability, evolution, genome, dimer, DNA molecule
References
1. Lehninger, A. Biohimiya [Biochemistry]. Moscow, 1976.
2. Patrushev, L. I. Ekspressiya genov [Expression of genes]. Moscow, 2000.
3. Singer, M., and P. Berg. Geny i genomy [Genes and Genomes]. Moscow, 1980.
4. Hohlov, A.R. Zhidkokristallicheskie polimery [Liquid Chrystal Polymeres]. Moscow, 1988.
5.Shabalkin, I.P., and P.I. Shabalkin. Teoreticheskie i ehksperimental'nye podhody k analizu biologicheskih sistem [Theoretical and experimental approaches to the analysis of biological systems]. Moscow, 2012.
6. Shabalkin, P.I. Fundamental'nye i prikladnye aspekty biomedicinskih issledovanij [Fundamental and applied aspects of biomedical research]. Moscow, 2013.
7. Watson J.D., Crick F.H.C. A Structure for Deoxyribose Nucleic Acid. Nature 1953; 171: 737-738.
