The effect of glaucoma surgical treatment on the state of retinal blood flow according to laser speckle flowgraphy

Petrov S. Yu.¹

Okhotsimskaya T. D.¹

Kosakyan S. M.¹

Markelova O. I.¹

1Helmholtz National Medical Research Center of Eye Diseases, Moscow, Russia

Markelova O. I.; e-mail: levinaoi@mail.ru

None declared.

The study had no sponsorship.

Ocular blood flow is one of the factors initiating the development and maintaining the progression of glaucomatous optic neuropathy. The purpose of this study is to investigate the effect of glaucoma surgery on retinal blood flow and the optic nerve head using laser speckle flowgraphy. Blood flow changes were measured in 40 patients with developed and advanced primary open-angle glaucoma (POAG) using the LSFG-RetFlow analyzer. The quantitative integral parameter of volumetric blood flow velocity (MBR) in the studied areas was analyzed one week before and 1.5 months after trabeculectomy. Statistically significant (p≤0.05) changes in MV and MT in the optic nerve head and peripapillary retina were observed in groups 1 and 2, with similar trends: an increase in 1.5 months after surgery. A significant inverse correlation between MV and MT and IOP parameters after trabeculectomy was observed. The study results indicate an improvement in hemodynamic parameters after trabeculectomy. However, the impact of ocular microcirculation on the prognosis of glaucomatous optic neuropathy progression requires further study.

primary open-angle glaucoma, intraocular pressure, ocular hemodynamics, retinal blood flow, trabeculectomy

10.29234/2308-9113-2025-13-4-121-129

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