Authors
Muzaffarova M. Sh.
Specialist-expert, Epidemiological Surveillance Department1, Resident, Chair for Epidemiology and Disinfectology2
Patyashina M. A.
Doctor of Medicine, Republic of Tatarstan Chief State Sanitary Doctor, Head of the Office1, Head, Chair for Epidemiology and Disinfectology2
1 - Department of Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing for the Republic of Tatarstan, Kazan, Russian Federation
2 - Kazan State Medical Academy of the Ministry of Health of Russia, Kazan, Russian Federation
Corresponding Author
Muzaffarova Milyausha; e-mail: Shamilevnamed@mail.ru
Funding
The study had no sponsorship.
Conflict of interest
None declared.
Abstract
Background. Healthcare-associated infections are an urgent problem that has a global spread, negative consequences for patients and medical workers, as well as for the state as a whole. The purpose of the study. To identify long-term trends in healthcare-associated infections in the Republic of Tatarstan. Materials and methods. A retrospective analysis of the epidemiological process of ISMP in the Republic of Tatarstan from 2000 to 2023 was carried out. Cases of intrauterine infections were not taken into account when calculating the morbidity rates of ISMP. Statistical processing was performed using the Statistica program version 10.0.1011.0 (StatSoft). The significance of the differences was calculated using the Student's t-criterion with the calculation of a 95% confidence interval by the Wald method. Differences were considered significant at p ≤ 0.05. Trend and approximation coefficient were calculated in Microsoft Excel. Results. There is a downward trend in the registration of ISMP in the Republic of Tatarstan. For many years, the most affected ISMS in the Republic of Tatarstan have been obstetric institutions, the average proportion is 61 ± 0.1%, while surgical hospitals account for only 9.9 ± 0.06%. The annually low incidence of ISMP in the Republic of Tatarstan is due to the underreporting of some nosologic forms: surgical site infections, urinary tract infections, pneumonia, etc. Analysis of Form No. 2 «Information on infectious and parasitic diseases» from 2005 to 2023 revealed that the list of names of nosological forms of ISMP increased by 86%. At the same time, 62.9 ± 16.8%, 95% CI [52.1 – 69.2] of the list of nosological forms according to Form No2 are registered annually in the Republic of Tatarstan. In the Republic of Tatarstan in 2023, the list of prevalent pathogens of ISMP includes bacteria of the genus Klebsiella spp. and Acinetobacter spp. Conclusion. The results of the analysis of the epidemiological situation of ISMP in the Republic of Tatarstan indicate the need for a risk-oriented approach to preventive and anti-epidemic measures. Further work is required to improve the system of epidemiological surveillance and measures to prevent infections associated with the provision of medical care.
Key words
infections related to medical care, Republic of Tatarstan
DOI
References
1. Brusina E.B., Zueva L.P., Kovalishena O.V. Infektsii, svyazannye s okazaniem meditsinskoy pomoshchi: sovremennaya doktrina profilaktiki. Chast' 1. Istoricheskie predposylki. [Healthcare-Associated Infections: Modern Doctrine of Prophylaxis. Part I. Historical Background.] Epidemiologiya i Vaktsinoprofilaktika [Epidemiology and Vaccinal Prevention] 2018; 17(5): 17-24, doi: 10.31631/2073-3046-2018-17-5-17-24 (In Russ.)
2. Pokrovskiy V.I., Akimkin V.G., Briko N.I., et al. Natsional'naya kontseptsiya profilaktiki infektsiy, svyazannykh s okazaniem meditsinskoy pomoshchi, i informatsionnyy material po ee polozheniyam. [National concept of prevention of healthcare-associated infections and information material on its provisions.] Nizhniy Novgorod: Remedium Privolzh'e, 2012. (In Russ.)
3. Brusina E.B., Zueva L.P., Kovalishena O.V., et al. Infektsii, svyazannye s okazaniem meditsinskoy pomoshchi: sovremennaya doktrina profilaktiki. Chast' 2. Osnovnye polozheniya. [Healthcare-Associated Infections: Modern Doctrine of Prophylaxis. Part II. Basic Concept.] Epidemiologiya i Vaktsinoprofilaktika [Epidemiology and Vaccinal Prevention] 2018; 17(6): 4-10, doi: 10.31631/2073-3046-2018-17-6-4-10 (In Russ.)
4. Akimkin V.G., Tutel'yan A.V. Aktual'nye napravleniya nauchnykh issledovaniy v oblasti infektsiy, svyazannykh s okazaniem meditsinskoy pomoshchi na sovremennom etape. [Current directions of scientific researches in the field of infections, associated with the medical care, at the present stage.] Zdorov’e Naseleniya i Sreda Obitaniya – ZNiSO [Public Health and Life Environment – PH&LE] 2018; (4): 46-50, doi: 10.35627/2219-5238/2018-301-4-46-50 (In Russ.)
5. WHO. Report on the Burden of Endemic Health Care-Associated Infection Worldwide. A systematic review of the literature. World Health Organization: 2011.
6. Orlova O.A., Yumtsunova N.A., Semenenko T.A., Karpov O.E., Rusakova E.V., Zotova A.A., Rusakov N.V., Kuzin S.N. Novye tekhnologii v komplekse meropriyatiy po nespetsificheskoy profilaktike infektsiy, svyazannykh s okazaniem meditsinskoy pomoshchi. [New technologies in complex of measures of nonspecific prophylaxis of healthcareassociated infection.] Gigiena i sanitariya [Hygiene and Sanitation] 2020; 99(10): 1055-1060, doi: 10.47470/0016-9900-2020-99-10-1055-1060 (In Russ.)
7. Morozov A.M., Morozova A.D., Belyak M.A., Zamana Yu.A., Zhukov S.V. Infektsii, svyazannye s okazaniem meditsinskoy pomoshchi. Sovremennyy vzglyad na problemu (obzor literatury). [Infections Associated with the Provision of Medical Care. Modern View on The Problem (Literature Review).] Vestnik novykh meditsinskikh tekhnologiy. Elektronnoe izdanie. [Journal of New Medical Technologies, eEdition] 2022; 16(4): 107-116, doi: 10.24412/2075-4094-2022-4-3-3 (In Russ.)
8. Voropaeva N.M., Nemchenko U.M., Grigorova E.V., et al. Etiologicheskaya struktura infektsiy, svyazannykh s okazaniem meditsinskoy pomoshchi, i antibiotikorezistetnost' osnovnykh vozbuditeley infektsiy. [Structure and Antibiotic Resistance of the Main Causative agents of Infections Associated with the Provision of Medical care.] Epidemiologiya i Vaktsinoprofilaktika [Epidemiology and Vaccinal Prevention] 2023; 22(1): 68-73, doi: 10.31631/2073-3046-2023-22-1-68-73. (In Russ.)
9. Tutel'yan A.V., Pisarev V.M., Gaponov A.M., Akimkin V.G. Perspektivy nauchnykh issledovaniy v oblasti profilaktiki infektsiy, svyazannykh s okazaniem meditsinskoy pomoshchi. [Prospects for researches in the prevention of healthcare-associated infections.] Epidemiologiya i infektsionnye bolezni. Aktual'nye voprosy [Epidemiology and Infectious Diseases. Current Items] 2014; (2): 45-51. (In Russ.)
10. Naygovzina N.B., Popova A.Yu., Biryukova E.E., Ezhlova E.B., Igonina E.P., Pokrovskiy V.I., et al. Optimizaciya sistemy mer bor'by i profilaktiki infekcij, svyazannyh s okazaniem medicinskoj pomoshchi v Rossijskoj Federacii. [Optimization of the system of measures to control and prevent health care-associated infections (HAIs) in the Russian Federation.] Orgzdrav. Vestnik VShOUZ [Healthcare Management News. Views. Education] 2018; (1): 17-26, doi: 10.24411/2411-8621-2018-00002 (In Russ.)
11. Morozov A.M. Askerov E.M., Zhukov S.V., Konstantinova M.I., Belyak M.A., Khorak K.I. Sovremennye sposoby profilaktiki vnutribol'nichnoy infektsii (obzor literatury). [New Ways to Prevent Nosocomial Infection (Literature Review).] Sanitarnyy vrach [Sanitary doctor] 2022; (7): 466-474, doi: 10.33920/med-08-2207-03 (In Russ.)
12. Brusina E.B., Barbarash O.L. Upravlenie riskom infektsiy, svyazannykh s okazaniem meditsinskoy pomoshchi (risk-menedzhment). [Risk Management of Infections Connected with Providing Medical Aid (Risk Management).] Meditsinskiy Al'manakh [Medical Almanac] 2015; (5): 22-25, doi: 10.18565/epidem.2020.10.1.109-110 (In Russ.)
13. Davydova M.A., Bryukhanova G.D., Gorodin V.N. Osobennosti sistemnogo podkhoda k profilaktike infektsiy, svyazannykh s okazaniem meditsinskoy pomoshchi, v Rossiyskoy Federatsii i za rubezhom. [Features of a Systematic Approach to the Prevention of Healthcare-Associated Infections in the Russian Federation and Abroad.] Epidemiologiya i Vaktsinoprofilaktika [Epidemiology and Vaccinal Prevention] 2023; 22(4): 140-148. doi: 10.31631/2073-3046-2023-22-4-140-148 (In Russ.)
14. Zhelnina T.P., Brusina E.B. Effektivnost' epidemiologicheskogo monitoringa v profilaktike infektsiy, svyazannykh s okazaniem meditsinskoy pomoshchi. [Efficiency of Epidemiological Monitoring in Prevention of Helthcare-Associated Infections] Epidemiologiya i Vaktsinoprofilaktika [Epidemiology and Vaccinal Prevention] 2019; 18(3): 84-88, doi: 10.31631/2073-3046-2019-18-3-84-88 (In Russ.)
15. Orlova O.A. Chastota rasprostraneniya i udel'nyy ves vnutribol'nichnykh infektsiy dykhatel'nykh putey v obshchey strukture infektsiy, svyazannykh s okazaniem meditsinskoy pomoshchi, v Chelyabinskoy oblasti i Rossiyskoy Federatsii. [Frequency of Spread and Relevant Part of Intrahospital Infections of Respiratory Airways in General Structure of Infections Connected with Providing Medical Aid in Chelyabinsk Region and the Russian Federation.] Meditsinskiy Al'manakh [Medical Almanac] 2015; (5): 50-54, doi: 10.47470/0016-9900-2020-99-10-1055-1060 (In Russ.)
16. Akimkin V.G., Tutel'yan A.V., Orlova O.A., et al. Infektsii, svyazannye s okazaniem meditsinskoy pomoshchi: informatsionnaya byulleten' za 2022 god. [Healthcare-associated infections: Fact Sheet 2022.] Moscow: FBUN TsNII Epidemiologii Rospotrebnadzora, 2023, doi: 10.36233/978-5-6048873-2-5 (In Russ.)
17. Brusina E.B., Kovalishena O.V., Tsigel'nik A.M. Infektsii, svyazannye s okazaniem meditsinskoy pomoshchi v khirurgii: tendentsii i perspektivy profilaktiki. [Healthcare-Associated Infections: Trends and Prevention Prospectives.] Epidemiologiya i Vaktsinoprofilaktika [Epidemiology and Vaccinal Prevention] 2017; (4): 73-80, doi: 10.31631/2073-3046-2017-16-4-73-80 (In Russ.)
18. Kosova A.A., Chalapa V.I. Infektsii, svyazannye s okazaniem meditsinskoy pomoshchi v statsionarakh Rossii: Opyt meta-analiza zabolevaemosti. [Infections Associated with Giving Medical Care in Hospitals of Russia: Experience of Meta Analysis of Morbidity.] Zdorov’e Naseleniya i Sreda Obitaniya – ZNiSO [Public Health and Life Environment – PH&LE] 2018; (12): 57-63, doi: 10.35627/2219-5238/2018-301-4-46-50 (In Russ.)
19. Yakovlev S.V. Suvorova M.P. Nozokomial'nye infektsii mochevyvodyashchikh putey. Glava iz knigi «Mezhdistsiplinarnye problemy v urologii». Pod red. P.V. Glybochko, Yu.G. Alyaev. [Nosocomial urinary tract infections. In Interdisciplinary problems in urology. Glybochko P.V., Alyaev Yu.G. (Eds.)] Moscow: Medforum, 2015. (In Russ.)
20. Aslanov B.I., Zueva L.P., Lyubimova A.V., Kolosovskaya E.N., Dolgij A.A., Os'mirko T.V. Epidemiologicheskoe nablyudenie za infektsiyami, svyazannymi s okazaniem meditsinskoy pomoshchi. Federal'nye klinicheskie rekomendatsii. [Epidemiologic surveillance of healthcare-associated infections. Federal clinical recommendations.] Moscow, 2014. (In Russ.)
21. Fedotova O.S., Zakharova Yu.A., Ostapchuk A.V., Bazhanova U.A., Zakharov A.A. Fenotipicheskiy profil' aktual'nykh polirezistentnykh sikvens-tipov (ST 1167, ST 944, ST 208) Acinetobacter baumannii. [Phenotypic Profile of Priority Multiresistant Ŕcinetobacter Baumannii Sequence Types (ST 1167, ST 944, ST 208).] Zhurnal mikrobiologii, epidemiologii i immunobiologii [Journal of Microbiology, Epidemiology and Immunobiology] 2021; 98(6): 639-647, doi: 10.36233/0372-9311-170 (In Russ.)
22. Kuz'menko S.A., Brezhneva N.I., Goncharov A.E., Tutel'yan A.V. Kharakteristika svoystv vnutribol'nichnoy populyatsii Klebsiella pneumoniae. [Features of Nosocomial Klebsiella Pneumoniae Population.] Fundamental'naya i klinicheskaya meditsina [Fundamental and clinical medicine] 2019; 4(2): 58-65, doi: 10.23946/2500-0764-2019-4-2-58-65 (In Russ.)