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Cannabis Use and Psychosis – Modern Views on the Problem. Narrative Synthesis

Journal «MEDICINA» ¹ 4, 2021, pp.76-100 (Reviews)

Authors

Kolgashkin A. J.
Senior Researcher1
ORCID 0000-0002-5592-4521

Nadezhdin A. V.
MD, PhD, Leading Researcher, Psychiatrist of the Consultative and Diagnostic Department1; Assistant Professor2
ORCID 0000-0003-3368-3170

Tetenova E. J.
MD, PhD, Leading Researcher, Psychiatrist of the Consultative and Diagnostic Department1
ORCID 0000-0002-9390-621X

Vdovin A. S.
MD, Head, Clinical Branch1

Yusupov A. A.
MD, Head, Emergency Addiction Treatment Department1

Sobornikova E. A.
MD, PhD, Psychotherapist1; Assistant Professor2

Alekseyuk V. V.
MD, Psychiatrist-Addiction Doctor, Emergency Addiction Treatment Department1
ORCID 0000-0002-6882-6875

Andryushin D. A.
MD, Psychiatrist-Addiction Doctor, Emergency Addiction Treatment Department1

Barsukova A. A.
MD, Psychiatrist, Emergency Addiction Treatment Department1

Deresh S. V.
MD, Psychiatrist-Addiction Doctor, Emergency Addiction Treatment Department1

Zajceva A. V.
MD, Psychiatrist-Addiction Doctor, Emergency Addiction Treatment Department1

Zverkov P. P.
MD, Psychiatrist-Addiction Doctor, Emergency Addiction Treatment Department1

Nadezhdin S. A.
MD, Researcher1

Nenasheva A. S.
MD, Psychiatrist-Addiction Doctor, Emergency Addiction Treatment Department1

Sivcov I. G.
Psychiatrist-Addiction Doctor, Emergency Addiction Treatment Department1

Sobolev S. S.
Psychiatrist-Addiction Doctor, Emergency Addiction Treatment Department1

1 - Moscow Research and Practical Centre on Addictions of Moscow Department of Public Health, Moscow, Russian Federation
2 - Russian Medical Academy of Continuous Professional Education, Moscow, Russian Federation

Corresponding Author

Kolgashkin Alexey; e-mail: krambol15@mail.ru

Conflict of interest

None declared.

Funding

The study had no sponsorship.

Abstract

Cannabis continues to be the most widely used drug worldwide. Recently, there has been two trends in the field: a liberalization of cannabis-related legislation in a number of countries, as well as an increase in the content of the psychoactive component in cannabis plant – tetrahydrocannabinol. The review covers a topic that has been little studied in Russian addiction science – cannabis use and associated psychotic disorders. Research materials: publications in the Pubmed and RSCI databases. Topics addressed include: cannabis use and psychotic disorders; alternative views on the causal relationship between cannabis use and psychotic disorders; gender specifics in the development of psychotic disorders; genetic predisposition to the development of psychotic disorders in cannabis users; problems with cannabis use in adolescence; possible reasons for using cannabis; suicidal behavior of cannabis users; relationship between cannabis and tobacco use; clinical aspects of treating cannabis users with psychotic disorders; promising areas of future studies. In the absence of domestic research on these topics, such a brief review may help addiction doctors to get a general idea of the modern state of the problem.

Key words

cannabis, psychosis, schizophrenia, tetrahydrocannabinol, cannabidiol, psychotic disorders

DOI

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