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Serum Albumin as Indicator of Intoxication in Athletes with Different Types of Training Process

Journal «MEDICINA» ¹ 2, 2017, pp.97-103 (Brief communications)

Authors

Semenova E. S.
postgraduate, Hospital Therapy Department1

Vasilenko V. S.
Doctor of Medicine, Professor, Head, Hospital Therapy Department1

Bubnova I. V.
PhD, doctor of sports medicine2

Gizha I. V.
PhD, doctor of sports medicine2

1 - Saint-Petersburg State Pediatric Medical University
2 - Saint-Petersburg Medical Exercises Dispensary

Abstract

In this research serum albumins were studied depending on the type of the training process. A total of 110 athletes (men and women) aged 15 to 20 years of different sports qualification (I sports category, Candidate Master of Sports and Master of Sports) were examined. Control group consisted of 34 persons of the same age and sex. Depending on the type of the training process 3 groups were defined: sports that develops mainly endurance (rowing); sports of complex nature (football, volleyball, handball and nordic combined); and complex coordinated sports (gymnastics). The research had shown that the most distinct decrease in total and effective albumin concentration is observed in men athletes in sport mainly developing endurance, due to the high demand for its detoxification capacity maintaining homeostasis.

Key words

serum albumin, endogenous intoxication, metabolism, athletes, adaptation

References

1. Afanaseva, I. A., and V. A. Taymazov. «The overtraining syndrome: endogenous intoxication and factors of innate immunity.» Uchenye zapiski universiteta im. P.F. Lesgafta, no. 12 (2011): 24-30.

2. Vasilenko, V. S. Stressornaya kardiomiopatiya u vysokokvalifitsirovannykh sportsmenov (patogenez, rannyaya diagnostika) [Stress cardiomyopathy in highly trained athletes (pathogenesis, early diagnosis]. Doctor of Medicine thesis, St. Petersburg State Pediatric Medical University, 2011. St Petersburg: SPbGPMA, 2011.

3. Komarova, M. N. «Stroenie molekuly al'bumina i ee svyazyvayushchikh tsentrov [The structure and binding centers of albumin molecule].» In Al'bumin syvorotki krovi v klinicheskoy meditsine [Serum albumin in clinical medicine], edited by Yu A. Gryzunov and G. E. Dobretsov, 28-51. Moscow: GEOTAR, 1998.

4. Luyk, A. I., and V. D. Lukyanchuk. Syvorotochnyy al'bumin i biotransport yadov [Serum albumin and biotransport of poisons]. Moscow: Meditsina, 1984.

5. Miller, Yu L., and G. E. Dobretsov. «Molecular basis of fluorescent method for the determination of binding capacity of serum albumin.» Klinicheskaya i laboratornaya diagnostika, no. 5 (1994): 20-22.

6. Stepuro, I. I. «. Vozdeystvie svobodnykh radikalov na syvorotochnyy al'bumin [The effects of free radicals on serum albumin].» In Al'bumin syvorotki krovi v klinicheskoy meditsine [Serum albumin in clinical medicine], edited by Yu A. Gryzunov and G. E. Dobretsov, 187-201. Moscow: GEOTAR, 1998.

7. Zaks, I. O., V. V. Ivleva, G. N. Meshcheryakov, G. E. Dobretsov et al. «Effektivnaya kontsentratsiya al'bumina i ego svyazyvayushchaya sposobnost' v otsenke tyazhesti kriticheskikh sostoyaniy [Effective concentration of albumin and its binding capacity in the evaluation of severity of critical conditions].» In Al'bumin syvorotki krovi v klinicheskoy meditsine [Serum albumin in clinical medicine], edited by Yu A. Gryzunov, 272-77. Moscow: GEOTAR, 1998.

8. Halliwell, Barry. «Albumin – An important extracellular antioxidant?» Biochemical Pharmacology 37, no. 4 (1988): 569-71. doi:10.1016/0006-2952(88)90126-8.

9. Kragh-Hansen, Ulrich. «Structure and ligand binding properties of human serum albumin.» Danish Medical Bulletin 37, no. 1 (1990): 57-84.

10. Peters, T. «Structure of serum albumin.» Advances in Protein Chemistry 37 (1985): 161-245.