Authors
Lorina L. V.
PhD. Associate professor, department of neurology, neurosurgery and medical genetics1
Dzhaparalieva N. T.
PhD. Assistant, department of neurology, neurosurgery and psychiatry2
Burshinov A. O.
PhD. Professor, department of neurology, neurosurgery and medical genetics1
1 - Ryazan State Medical University named after academician I.P. Pavlov, Ryazan, Russian Federation
2 - Kyrgyz state medical Institute of retraining and advanced training, Bishkek, Kyrgyzstan
Corresponding author
Lorina L. V., E-mail ladlorin@yandex.ru
Abstract
Aim. Analysis of quality of life indicators in patients with different types of multiple sclerosis and their relationship with disease duration, degree of disability and the damage of functional systems. Material and Methods. We examined 200 patients with different types of multiple sclerosis course. The quality of life was surveyed using the SF-36 questionnaire. Neurological status was assessed according to Kurtzke's functional systems scale and EDSS disability score scale. Results. In patients with MS, all quality of life indicators significantly decreased, with maximum effect in physical and emotional functioning. The deterioration in quality of life begins in the early stages of the disease (up to 5 years). With prolonged disease duration, severity of the course and progressive disability, significant decrease in physical and emotional functioning is observed, at the same time social functioning is preserved. Conclusion. Life quality parameters stronger correlate to degree of disability as compared to disease duration. The relationship between indicators of physical health with the duration of the disease and the degree of disability is more significant than that of mental health. In the primary-progressive type of disease course, these changes develop in a shorter time, and are more pronounced than in other types of disease course.
Key words
multiple sclerosis, quality of life, clinical type of multiple sclerosis, EDSS disability scale, functional systems' scale
References
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