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Violations of system connections in the organism, by the example of transplanted tumors

Journal «MEDICINA» ¹ 2, 2016, pp.64-72 (Research)

Authors

Shabalkin I. P.
Doctor of Biology1

Grigorieva E. Yu.
Doctor of Biology1

Gudkova M. V.
PhD1

Stukalov Yu. V.
PhD1

Shabalkin P. I.
PhD2

1 - Russian Cancer Research Center named after N.N. Blokhin, Moscow
2 - Scientific and Clinical Center for Pediatric Oncology, Hematology and Immunopathology named after Dmitri Rogachov, Moscow

Abstract

By a method of a cytophotometry on 3 pilot models of swellings of a solid type is shown that tumor`s influence to the organism includes 2 stages: 1stage – tumor`s direct influence to the target-organ; 2 stage – indirect tumor`s influence, which consists in the change of functional relations between other organs cells populations under the influence of transformed cells of the damaged target-organ.

Key words

tumor, target, transformed cell

References

1. Grebennikova O.P, Features of tumor growth. Classification of tumors. The concept of the clinical groups. Oncology for medical practitioners. Moscow, 2009. Print.

2. Derizhanova I.S, The significance of endocrine differentiation of cancer in lung, stomach, colon and small intestine, pancreas. Proceedings of the 1st Congress of CIS Oncologists. Vol. 1. Moscow, 1996. Print.

3.Kaveckij R.E, The interaction of the body and tumors. Kiev, 1977. Print.

4. Speranskij A.D, Elements of building a theory of medicine. Moscow – Leningrad, 1935. Print.

5. Fel' V.Ya, Cytology. 5 (1990): 407-421.

6. Shabalkin I.P, Cytology. 1 (1998): 107-116.

7. Shabalkin I.P., Shabalkin P.I, Theoretical and experimental approaches to the analysis of biological systems. Moscow, 2012. Print.

8. Shabalkin P.I, Fundamental and applied aspects of biomedical research. Moscow, 2013. Print.

9. Shapot V.S, Biochemical aspects of tumor growth. Moscow, 1975. Print.

10. Shvemberger I.N, Cancer and cell differentiation. Leningrad, 1976. Print.