Authors
Rud'ko E. A.
candidate of pharmaceutical sciences, Head of Department1
Antochin A. M.
candidate of engineering sciences, Deputy Director for Science1
Bykova E. M.
junior researcher1
Rumiantseva E. V.
junior researcher1
1 - Scientific Center «Signal»
Abstract
The article presents the results of experimental studies on the development of optimal composition and technology of complex suppositories for chronic prostatitis' treatment, which contain crystalline bear's bile and dry extract derived from dead bee bodies. Standartization of the developed drugs was established. It is found that obtained suppositories accord to organoleptic, physical, chemical and technological characteristics meet the requirements of the normative documentation.
Key words
suppositories, technology, chronic prostatitis, bear's bile, extract derived from dead bee bodies
References
1. Al-Shukri S.H. Solihov D.N, «Modern methods of treatment of chronic prostatitis (review of literature).» Nefrologiya. 2 (2009): 86-91.
2. Averina T.V. Bereznyakova M.E, «Prostatitis protective activity of »Liproprost« suppositories on the model of turpentine prostatitis.» Zaporozhskij medicinskij zhurnal. 3 (2010): 89-91.
3. Berikashvili Z.N. Boer I.V, «Antibacterial activity of extracts of Apis Mellifera.» Vestnik KrasGAU. 3 (2009): 197-199.
4. Tereshin A.T. et al. «Combined vibration, magnet and laser therapy in complex non-pharmacological correction of erectile dysfunction in patients with chronic prostatitis.» Vestnik novyh medicinskih tekhnologij. 4 (2012): 67.
5. Russian State Pharmacopoeia XII edition (part 2). Moscow: Medicina, 2010. Print.
6. Russian State Pharmacopoeia XIII edition (Vol.2). Available at: http://193.232.7.120/feml/clinical_ref/pharmacopoeia_2/HTML
7. Gricenko V.I. Ruban E.A. Pulyaev D.S, «Substantiation of technology and thermal gravimetric analysis suppositories with vegetable raw materials for the treatment of prostate disease.» Fundamentalnye issledovaniya. 3 (2014): 128-132.
8. Gurckoj R.A, Physical factors and medicinal suppository in the treatment of patients with chronic bacterial prostatitis. PhD Thesis. Moscow: 2006. Print.
9. Dzyuba V.F. Polkovnikova Yu.A. Slivkin A.I, Soft formulations: a teaching guide on the subject Pharmaceutical Technology. Available at: http://www.pharm.vsu.ru›sources/atlfaiz3.pdf
10. Korotkov V.A, «Comparative analysis of prostatoprotektor market in Kazakhstan, Russia and Ukraine.» Vestnik JuKGFA. 3 (2013): 6-10.
11. Krasnyuk I.I. Mihajlova G.V, Workshop on technology of medicinal forms: a textbook. Moscow: Academia, 2006. Print.
12. Krupin A.V. Krupin V.N. Artifeksova A.A, «The value of the microbial factor in the pathogenesis of chronic bacterial prostatitis.» Medicinskij vestnik Bashkortostana. 2 (2013): 106-110.
13. Kul'chavenya E.V., Nejmark A.I. Prostatitis. Moscow: GEOTAR-Media, 2010. Print.
14. Medicinal properties of bear bile. Available at: http://bakumedinfo.com/index.php?option=com_content&id=6208:2013-01-04-10-16-52
15. Nemcev S.V. et al. «Chitosan from Apis Mellifera – a new product of beekeeping.» Pchelovodstvo. 5 (2001): 50-51.
16. Osipov P.G, « Alternative correction of blood flow in the prostate during male menopause, combined with chronic prostatitis.» Nauchnye vedomosti BelGU, Seriya Medicina. Farmaciya. 11 (2014): 19-23.
17. Bratchikov O.I. et al. «Increased clinical and immunological effectiveness of complex treatment of patients with chronic prostatitis.» Urologiya. 4 (2008): 44-49.
18. Razmahnin V.E, «The bile of wild animals – a valuable medicinal product.» Ohota i ohotnich'e hozyajstvo. 7 (1988): 14-15.
19. Markova I.I. et al. Development of composition and technology of suppositories for the treatment of proctologic diseases. Proceedings of X International Conference «Pharmacological foundations of modern medicine, the problems and their solutions. Medical and social ecology of personality: state and prospects.» Minsk, 2012. Print.
20. Korotkov V.A. et al. «Development of methods for qualitative and quantitative analysis of suppositories using extract of Maclura pomifera.» Aktual'nye voprosy farmacevticheskoj nauki i praktiki. 2 (2014): 27-30.
21. Lopatkin N.A, (Editor) Rational pharmacotherapy in urology: a guide for practitioners. Moscow: Littera, 2006. Print.
22. SanPiN 2.3.2 1078-01 item 1.10.7.1
23. Certificate of conformity ¹ ÐÎÑÑ RU.0001.10Àß79
24. Certificate of conformity ¹ BOSTI/POCC RU.0001.040007C 11-67
25. Sitdykova M.E., Perchatkin V.A, «Experience with prostanorm drug in the treatment of patients with chronic prostatitis.» Kazanskij medicinskij zhurnal. 4 (2002): 305-306.
26. Smirnov V.A, «Drug therapy of chronic prostatitis.» FARMindeks-Praktik. 10 (2006): 46-55.
27. Bear bile. Specifications. STO 222401001-003-2012.
28. Ermakova N.Yu. et al. «The technology for producing an extract of Apis Mellifera.» Biotekhnologiya. 2 (2010): 89-95.
29. TU 9882-005-60758298-10.
30. Harisova N.M, « Physico-chemical properties of bile from animals of different species and humans.» Biologiya. 8 (2006): 57-61.
31. Korpachev V.V, (Editor) Healing fauna. Moscow: Nauka, 1989. Print.
